Candida albicans (Robin) Berkhout 拉丁名
(ATCC? MYA-2876?) 統(tǒng)一編號
Strain Designations SC5314
Biosafety Level 生物安全等級 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format 提供形式 frozen
Storage Conditions 生長條件
Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Type Strain 模式菌種 no
Preceptrol? no
Genome Sequenced Strain Yes
Comments 注釋 Genome sequencing strain
(Stanford Genome Technology Center, Stanford University, USA;
China pharmaceutical University, China). Sequenced mitochondrial genome.
Medium 培養(yǎng)基 ATCC? Medium 200: YM agar or YM broth
ATCC? Medium 28: Emmons' modification of Sabouraud's agar
Growth Conditions 生長條件
Temperature 培養(yǎng)溫度: 25°C to 30°C
Atmosphere 需氧情況: Typical aerobic
Sequenced Data 18S ribosomal RNA gene, partial sequence;
internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed
spacer 2, complete sequence; and 26S ribosomal RNA gene, partial sequence ACCTGCGGAAGGATCATTACTGATTTGCTTAATTGCACCACATGTGTTT
TTCTTTGAAACAAACTTGCTTTGGCGGTGGGCCCAGCCTGCCGCCAGAG
GTCTAAACTTACAACCAATTTTTTATCAACTTGTCACACCAGATTATTACTAA
TAGTCAAAACTTTCAACAACGGATCTCTTGGTTCTCGCATCGATGAAGAACG
CAGCGAAATGCGATACGTAATATGAATTGCAGATATTCGTGAATCAT
CGAATCTTTGAACGCACATTGCGCCCTCTGGTATTCCGGAGGGCATGC
CTGTTTGAGCGTCGTTTCTCCCTCAAACCGCTGGGTTTGGTGTTGAGCA
ATACGACTTGGGTTTGCTTGAAAGACGGTAGTGGTAAGGCGGGATCGCTTTG
ACAATGGCTTAGGTCTAACCAAAAACATTGCTTGCGGCGGTAACGTCCA
CCACGTATATCTTCAAACTTTGACCTCAAATCAGGTAGGACTACCCGCTGAAC
TTAAGCATATCAATA D1D2 region of the 26S ribosomal RNA gene ATATCAATAAGCGGAGGAAAAGAAACCAACAGGGATTGCCTCAGTAGC
GGCGAGTGAAGCGGCAAAAGCTCAAATTTGAAATCTGGCGTCTTTGGCGT
CCGAGTTGTAATTTGAAGAAGGTATCTTTGGGCCCGGCTCTTGTCTATGTTCC
TTGGAACAGGACGTCACAGAGGGTGAGAATCCCGTGCGATGAGATGA
CCCGGGTCTGTGTAAAGTTCCTTCGACGAGTCGAGTTGTTTGGGAATGCA
GCTCTAAGTGGGTGGTAAATTCCATCTAAAGCTAAATATTGGCGAGAGA
CCGATAGCGAACAAGTACAGTGATGGAAAGATGAAAAGAACTTTGAAAAG
AGAGTGAAAAAGTACGTGAAATTGTTGAAAGGGAAGGGCTTGAGATCAGA
CTTGGTATTTTGCATGCTGCTCTCTCGGGGGCGGCCGCTGCGGTTTAC
CGGGCCAGCATCGGTTTGGAGCGGCAGGATAATGGCGGAGGAATG
TGGCACGGCTTCTGCTGTGTGTTATAGCCTCTGACGATACTGCCAGCCTAGA
CCGAGGACTGCGGTTTTTACCTAGGATGTTGGCATAATGATCTTAAGTCGCCCGTCTTG
Name of Depositor 寄存人 YR Thorstenson, Bristol-Myers Squibb Co.
Special Collection Yeast Genetic Research Resource
Chain of Custody 來源國家 ATCC <-- YR Thorstenson <-- PT Magee <-- S Scherer<-- Bristol-Myers Squibb Co.
Isolation Clinical specimen - human
Cross References
Nucleotide (GenBank) : KU729070 ITS including 5.8S rRNA gene Complete Genome (GenBank) : AACQ00000000 Candida albicans SC5314, whole
genome shotgun sequencing project.
References Fonzi WA, Irwin MY. Isogenic strain construction and gene mapping in
Candida albicans. Genetics 134: 717-728, 1993.
Yvonne R Thorstenson, personal communication Jones T, et al. The diploid genome sequence
of Candida albicans. Proc. Natl. Acad. Sci. USA 101: 7329-7334, 2004.
Anderson JB, et al. Infrequent genetic exchange and recombination in the mitochondrial
genome of Candida albicans. J. Bacteriol. 183: 865-72, 2001. PubMed: 11208783
Wang H, et al. A fungal phylogeny based on 82 complete genomes using the
composition vector method. BMC Evol. Biol. 9: 195, 2009. PubMed: 19664262
Mishra PK, Baum M, Carbon J. DNA methylation regulates phenotype-dependent transcriptional activity in Candida albicans. Proc Natl Acad Sci USA 108: 11965-11970, 2011. PubMed: 21730141
Zhang N, et al. Distribution of mutations distinguishing the most prevalent disease-causing Candida albicans genotype from other genotypes. Infect. Genet. Evol. 9: 493-500, 2009. PubMed: 19460314
Wimalasena TT, et al. Impact of the unfolded protein response upon genome-wide expression patterns, and the role of Hac1 in the polarized growth, of Candida albicans. Fungal Genet. Biol.45: 1235-1247, 2008. PubMed: 18602013
Mora-Montes HM, et al. Endoplasmic reticulum alpha-glycosidases of Candida albicans are required for N glycosylation, cell wall integrity, and normal host-fungus interaction. Eukaryot Cell 6: 2184-2193, 2007. PubMed: 17933909
Zhao X, et al. Analysis of ALS5 and ALS6 allelic variability in a geographically diverse collection of Candida albicans isolates. Fungal Genet Biol 44: 1298-1309, 2007. PubMed: 17625934
Selmecki A, Forche A, Berman J. Aneuploidy and isochromosome formation in drug-resistant Candida albicans. Science 313: 367-370, 2006. PubMed: 16857942
